Clinspire - AI-powered Clinical Trial Matching Platform

Clinspire - AI-powered Clinical Trial Matching Platform

Co-designed an AI trial-matching platform with 4+ Mayo Clinic physicians featuring eligibility visuals, simplified medical jargon, and empathetic chatbot onboarding to tackle 85% enrollment failure.

AI generated cover image
AI generated cover image
AI generated cover image
AI generated cover image

Year

Year

Year

2025

2025

2025

Client

Client

Client

Mayo Clinic

Mayo Clinic

Mayo Clinic

Team

Team

Team

5 UX/UI Designers, 4 Doctors, 1 Mentor

5 UX/UI Designers, 4 Doctors, 1 Mentor

5 UX/UI Designers, 4 Doctors, 1 Mentor

Project Overview

Clinical trials are essential for advancing cancer treatment and precision medicine. Our AI-powered clinical trial matching platform is designed with a patient-first approach, featuring an intuitive, conversational interface that guides users clearly and empathetically through the process.

The Challenges

  1. Over 85% of clinical trials struggle with timely patient recruitment, delaying access to critical therapies.

  2. Complex matching of eligibility criteria creates confusion and barriers for both patients and providers.

  3. Low digital literacy limits patient engagement with online trial-matching tools.

  4. Dense medical jargon and complex terminology on trial platforms confuse patients and contribute to high drop-off rates.

  5. Distrust in AI tools reduces willingness to use digital matching solutions.

How do we create a clinical trial matching experience that is simple, trustworthy, and accessible?

How do we create a clinical trial matching experience that is simple, trustworthy, and accessible?

User Needs

Need for Efficient and Timely Patient Recruitment

Users need streamlined processes that accelerate matching and enrollment to reduce delays in accessing therapies.

Need for Efficient and Timely Patient Recruitment

Users need streamlined processes that accelerate matching and enrollment to reduce delays in accessing therapies.

Need for Efficient and Timely Patient Recruitment

Users need streamlined processes that accelerate matching and enrollment to reduce delays in accessing therapies.

Need for Simplified and Clear Eligibility Matching

Users need eligibility criteria to be presented in an understandable, concise way to minimize confusion and barriers for patients and providers.

Need for Simplified and Clear Eligibility Matching

Users need eligibility criteria to be presented in an understandable, concise way to minimize confusion and barriers for patients and providers.

Need for Simplified and Clear Eligibility Matching

Users need eligibility criteria to be presented in an understandable, concise way to minimize confusion and barriers for patients and providers.

Need for Accessible and User-Friendly Digital Tools

Users with varying levels of digital literacy need intuitive, easy-to-navigate platforms that facilitate engagement without technical difficulties.

Need for Accessible and User-Friendly Digital Tools

Users with varying levels of digital literacy need intuitive, easy-to-navigate platforms that facilitate engagement without technical difficulties.

Need for Accessible and User-Friendly Digital Tools

Users with varying levels of digital literacy need intuitive, easy-to-navigate platforms that facilitate engagement without technical difficulties.

Need for Clear, Jargon-Free Communication

Users require trial information to be conveyed in plain language, avoiding dense medical terminology, so they can make informed decisions without frustration.

Need for Clear, Jargon-Free Communication

Users require trial information to be conveyed in plain language, avoiding dense medical terminology, so they can make informed decisions without frustration.

Need for Clear, Jargon-Free Communication

Users require trial information to be conveyed in plain language, avoiding dense medical terminology, so they can make informed decisions without frustration.

Need for Transparency and Trustworthiness in AI

Users need assurance about data privacy, accuracy, and fairness in AI-driven matching tools to build confidence and willingness to use digital platforms.

Need for Transparency and Trustworthiness in AI

Users need assurance about data privacy, accuracy, and fairness in AI-driven matching tools to build confidence and willingness to use digital platforms.

Need for Transparency and Trustworthiness in AI

Users need assurance about data privacy, accuracy, and fairness in AI-driven matching tools to build confidence and willingness to use digital platforms.

Business Goals

Increase Patient Recruitment Rates

Boost eligible patient enrollment in cancer clinical trials by streamlining the matching process.

Increase Patient Recruitment Rates

Boost eligible patient enrollment in cancer clinical trials by streamlining the matching process.

Increase Patient Recruitment Rates

Boost eligible patient enrollment in cancer clinical trials by streamlining the matching process.

Enhance Platform Engagement

Deliver a personalized, supportive experience to improve user retention and satisfaction.

Enhance Platform Engagement

Deliver a personalized, supportive experience to improve user retention and satisfaction.

Enhance Platform Engagement

Deliver a personalized, supportive experience to improve user retention and satisfaction.

Strengthen Brand Trust

Prioritize transparency, data security, and empathetic design to build a trusted reputation.

Strengthen Brand Trust

Prioritize transparency, data security, and empathetic design to build a trusted reputation.

Strengthen Brand Trust

Prioritize transparency, data security, and empathetic design to build a trusted reputation.

Accelerate Drug Development

Facilitate faster, more diverse clinical trial enrollment to support efficient drug testing and delivery.

Accelerate Drug Development

Facilitate faster, more diverse clinical trial enrollment to support efficient drug testing and delivery.

Accelerate Drug Development

Facilitate faster, more diverse clinical trial enrollment to support efficient drug testing and delivery.

Research Insights

We began with affinity mapping to identify key user pain points, followed by competitive analysis to benchmark existing solutions. Targeted interviews with clinicians and caregivers then validated these findings and guided our design decisions.

Confusing Medical Jargon Drove Users Away

What we learned:

What we learned:

Through qualitative analysis, I found that complex terminology on trial listings and individual trial pages consistently confused users. This led to frustration and higher drop-off rates during enrollment.

Through qualitative analysis, I found that complex terminology on trial listings and individual trial pages consistently confused users. This led to frustration and higher drop-off rates during enrollment.

How we acted:
How we acted:

We worked with clinical experts to rewrite key sections in plain language. This made trial information more accessible and directly reduced user confusion and drop-off.

We worked with clinical experts to rewrite key sections in plain language. This made trial information more accessible and directly reduced user confusion and drop-off.

Lack of Personalized Matching and Poor Navigation

What we learned:

What we learned:

Benchmarking top platforms ClinicalTrials.gov, TrialJectory, Antidote, and TrialX, revealed that none personalize trial results for user profiles. Users also faced limited filtering options (e.g., study status, type) and a lack of automation.

Benchmarking top platforms ClinicalTrials.gov, TrialJectory, Antidote, and TrialX, revealed that none personalize trial results for user profiles. Users also faced limited filtering options (e.g., study status, type) and a lack of automation.

How we acted:
How we acted:

We designed a guided intake flow that gathered user data upfront, enabling personalized trial recommendations and relevant filters based on individual eligibility criteria. Usability tests showed users found suitable trials faster and felt more confident in their selections.

We designed a guided intake flow that gathered user data upfront, enabling personalized trial recommendations and relevant filters based on individual eligibility criteria. Usability tests showed users found suitable trials faster and felt more confident in their selections.

Overwhelming Eligibility Criteria
What we learned:
What we learned:

Stakeholder interviews revealed that patients were overwhelmed by dense eligibility requirements and confusing medical language, even clinicians flagged this as a barrier.

Stakeholder interviews revealed that patients were overwhelmed by dense eligibility requirements and confusing medical language, even clinicians flagged this as a barrier.

How we acted:
How we acted:

We prioritized redesigning the eligibility section, simplifying both the content and visual hierarchy, so users could quickly understand if a trial was right for them.

We prioritized redesigning the eligibility section, simplifying both the content and visual hierarchy, so users could quickly understand if a trial was right for them.

Step back

Once done talking to doctors, we realized that focusing on both doctor and patient flows was diverting us from our main goal, so we shifted our attention to the patient flow.

Ideation

After gathering research insights, we mapped the patient user flow to pinpoint exactly where users encountered challenges. Addressing these pain points enabled us to design a more streamlined and effective experience.

Clinspire user flow
Clinspire user flow
Clinspire user flow
Clinspire user flow

Initial Wireframes

Given the current complexities in clinical trial matching, we developed wireframes grounded in user flows and research insights to address key challenges such as confusing medical jargon, unclear eligibility, and accessibility barriers. This approach enabled us to create a more intuitive and user-friendly experience for patients.

Wireframes of web pages and app screens, showing website design and layout.
Wireframes of web pages and app screens, showing website design and layout.
Wireframes of web pages and app screens, showing website design and layout.
Wireframes of web pages and app screens, showing website design and layout.

Final Designs

We started by designing the platform for both doctors and patients, but realized that creating a separate flow for doctors was diverting us from our main goal, improving trial matching for patients. Based on this, and feedback from clinicians, we took a step back and shifted our focus to a patient-centric approach.

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Clinspire.com

Clinspire.com

Medical Jargon Simplified with AI

Medical Jargon Simplified with AI

Clear Eligibility Status

Clear Eligibility Status

We organized eligibility criteria into clear sections Met, Unmet, and Need Review, so users could easily understand their status and progress, effectively reducing confusion.

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Clinspire.com

Clinspire.com

By simplifying medical jargon with AI and presenting clear eligibility criteria, we make information accessible to users with varying health literacy, helping them quickly understand their status.

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Clinspire.com

Clinspire.com

Users can opt for AI-guided onboarding, making the process easier for those who are fatigued, visually impaired, or prefer not to complete forms manually.

Users can opt for AI-guided onboarding, making the process easier for those who are fatigued, visually impaired, or prefer not to complete forms manually.

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Clinspire.com

Clinspire.com

Testimonials and community insights can help users trust the platform; future enhancements like transparent AI explanations, privacy assurances, and human oversight will further ease concerns.

Testimonials and community insights can help users trust the platform; future enhancements like transparent AI explanations, privacy assurances, and human oversight will further ease concerns.

Final Prototype

Outcomes

Clinspire’s design is expected to drive the following positive outcomes, making clinical trial participation more human-centered and equitable.

Outcomes for clinspire
Outcomes for clinspire
Outcomes for clinspire
Outcomes for clinspire

My Learnings

  • Empathy and flexibility are essential when designing for vulnerable populations.

  • Continuous engagement with stakeholders, especially clinicians and caregivers, leads to more inclusive and effective solutions.

  • Visual clarity and transparent AI explanations greatly improve user trust and comprehension.

  • Iterative prototyping and real-world feedback are key to refining digital health tools.

Future Enhancement: Due to confidentiality and medical restrictions, we were unable to interview real patients directly. In future iterations, collaborating with patients will be a priority to gain deeper, firsthand insights and further validate our design decisions.

Group photo of eleven young professionals posing for a picture in a modern office space. A large screen displays a video conference of multiple participants behind them.
Group photo of eleven young professionals posing for a picture in a modern office space. A large screen displays a video conference of multiple participants behind them.
Group photo of eleven young professionals posing for a picture in a modern office space. A large screen displays a video conference of multiple participants behind them.
Group photo of eleven young professionals posing for a picture in a modern office space. A large screen displays a video conference of multiple participants behind them.